https://doi.org/10.51514/JSTR.5.4.2023.26-33
Priyanka and Amita Sarkar
ABSTRACT
Background: Moringa oleifera, commonly known as the drumstick tree, is renowned for its medicinal properties and nutritional value. Recent studies have hinted at its potential as a natural protective agent against various health issues, particularly those associated with oxidative stress.
Objective: This research aimed to systematically investigate the efficacy of Moringa oleifera in reducing oxidative stress markers, with a specific focus on malondialdehyde (MDA) levels, to determine its potential as a protective agent.
Methods: A randomized controlled trial was conducted with 100 participants divided into two groups: one receiving Moringa oleifera extract and the other a placebo. Blood samples were collected at baseline and after an 8-week treatment period to measure MDA levels. The study employed rigorous statistical analyses, including paired and independent t-tests, to evaluate the impact of Moringa oleifera on oxidative stress.
Results: The findings indicated a non-significant trend toward reduced MDA levels in the treatment group compared to the control group, suggesting a potential protective effect of Moringa oleifera against oxidative stress.
Conclusion: While the study revealed a promising direction in the use of Moringa oleifera as a protective agent, the results were not statistically significant. Further research with larger sample sizes and varied dosages is recommended to conclusively determine the efficacy of Moringa oleifera in combating oxidative stress.
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Keywords: Moring, stress, malondialdehyde, trial, protective agent, antioxidant etc.